Regenerative Medicine includes the use of non-surgical injection procedures for the permanent repair of damaged tendons, ligaments, joints and skin.
This includes Regenerative Injection Therapy (RIT) where a needle and irritant solution is inserted directly into degenerated tissue, causing controlled tissue disruption and bleeding. Ligaments and tendons have poor blood supply and takes longer to heal than other tissue. Three different substances can be used as an "irritant"--Dextrose, Platelet Rich Plasma (PRP), or Stem Cells. It is postulated that a joint is as strong as its weakest ligament.
With dextrose Prolotherapy, a hypertonic solution is used, which then mimics an acute injury with no tissue insult. Low grade inflammation at the site of the ligament or tendon weakness "tricks" the body into initiating a new healing cascade. This is elicited by the release of endogenous growth factors with the attraction of platelets. A cytokine known as platelet-derived growth factor (PDGF) stimulates cell replication, promotes new blood vessel growth, epithelization, and granulation tissue formation. The ultimate goal is deposition of new, more organized collagen, resulting in the restoration of function. For optimal results, the medical/health team must approach the patient in a comprehensive manner by correcting faulty biomechanics and addressing systemic inflammation and metabolic dysfunction. All these factors combined with oral, IM or IV nutrient supplementation will foster the perfect microenvironment for tissue regeneration to occur.